HCG Peptide

A pregnancy hormone with a real medical history and a fake one running alongside it.

HCG, human chorionic gonadotropin, is a heterodimeric glycoprotein hormone of 237 amino acids in two separately encoded chains: a 92-residue alpha chain shared with LH, FSH and TSH, and a 145-residue beta chain that confers specificity. The molecule is approved and has been marketed in Canada as Chorionic Gonadotropin for Injection USP under DIN 02247459 since 2004, and its FDA-approved label states in capital letters that it is not effective for weight loss.

This one has two stories and only one of them is real. Worth getting them apart before anything else.

The real one: hCG is a 237-residue glycoprotein hormone made by the placenta. It is what a pregnancy test detects. Its characterisation is foundational reproductive endocrinology and it carries genuine regulatory approvals in fertility and endocrine medicine.

That proposal became a protocol, the protocol became an industry, and the industry has outlived the evidence by about seventy years.

Its approved indications are fertility and endocrine. Not one of them is a slimming indication.

We sell it as a research material and we are going to be blunt about which of those two stories has support behind it.

Two chains, one of them shared with three other hormones entirely.

Here's a genuinely odd bit of biology. hCG is not one chain, it's two, stuck together.

And the first chain isn't even its own. The alpha subunit is shared, identically, with several other hormones in your body.

So the specificity of this hormone lives in one half of it. That is not a design anybody would choose from scratch, it's the result of a family of hormones evolving off a shared part.

It is also why measuring it is fiddly and why assays have to be beta-specific to mean anything.

Here's the honest part. The receptor pharmacology here is well characterised, in a well-studied clinical area, and none of that has anything to do with the reason most people search for it.

A hormone having a solid file for one purpose is not evidence for a different purpose. That confusion is the entire commercial history of this compound.

Genuine approvals in one area. Seven decades of noise in another.

Two literatures, wildly different in quality, and people quote whichever one suits them.

The first is real. Decades of reproductive endocrinology, regulatory approvals, established clinical use under supervision, and a well-understood mechanism.

The pattern in that second literature is consistent and it is not flattering. Controlled comparisons keep failing to separate it from placebo once the severe caloric restriction is accounted for, because the restriction was always doing the work.

And regulators have been explicit that the slimming use is not among its approved indications, which is an unusually direct thing for a regulator to bother saying.

A compound can have an excellent research file and a worthless reputation at the same time. This is the clearest example of that on the whole shelf.

Read the label before anything we write. The FDA-approved labelling for this product opens its indications section with a capitalised statement that HCG has not been demonstrated effective for obesity and that there is no substantial evidence it increases weight loss beyond caloric restriction. That is the manufacturer own required wording and it is more authoritative than anything on this page.

Same day out of British Columbia. Our building, our cold packs, our people, and nothing sitting in a customs queue while you refresh a tracking page.

Prohibited in sport, for men. WADA 2026 section S2.2.1 covers testosterone-stimulating peptides in males and names chorionic gonadotrophin explicitly. Prohibited at all times for male athletes. The in males qualifier is in the section heading, since it is a normal pregnancy hormone in women.